Article Dans Une Revue Clinica Chimica Acta Année : 2025

A French multicenter analytical evaluation of the automated Lumipulse G sNfL blood assay (Fujirebio®) and its comparison to four other immunoassays for serum neurofilament light chain assessment in clinical settings

Aurélie Bedel
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Sylvain Lehmann

Résumé

Measurement of serum neurofilament light chain (sNfL) protein is becoming a key biomarker for many neurological diseases. Several immunoassays have been developed to meet these clinical needs, revealing significant differences in terms of variability and results. Here, we propose a French multicenter comparison of 5 sNfL assays.
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hal-04796015 , version 1 (24-01-2025)

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Etienne Mondésert, Susanna Schraen-Maschke, Isabelle Quadrio, Olivier Bousiges, Damien Bouvier, et al.. A French multicenter analytical evaluation of the automated Lumipulse G sNfL blood assay (Fujirebio®) and its comparison to four other immunoassays for serum neurofilament light chain assessment in clinical settings. Clinica Chimica Acta, 2025, 565, pp.120007. ⟨10.1016/j.cca.2024.120007⟩. ⟨hal-04796015⟩
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