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Deep learning enabled label-free microfluidic droplet classification for single cell functional assays

Thibault Vanhoucke , Angga Perima , Lorenzo Zolfanelli , Pierre Bruhns , Matteo Broketa
Frontiers in Bioengineering and Biotechnology, 2024, 12, pp.1468738. ⟨10.3389/fbioe.2024.1468738⟩
Article dans une revue pasteur-04703977v1
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Inhibitory IgG Receptor-Expressing Cells: The Must-Have Accessory for Anti-CD40 Immunomodulatory mAb Efficacy

Pierre Bruhns , Jean-Luc Teillaud
Cancer Cell, 2016, 29 (6), pp.771-773. ⟨10.1016/j.ccell.2016.05.009⟩
Article dans une revue pasteur-02578652v1
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Oxidized hemoglobin triggers polyreactivity and autoreactivity of human IgG via transfer of heme

Cyril Planchais , Remi Noe , Marie Gilbert , Maxime Lecerf , Srini V Kaveri , et al.
Communications Biology, 2023, 6, pp.168. ⟨10.1038/s42003-023-04535-5⟩
Article dans une revue hal-03988037v1
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High seroprevalence but short-lived immune response to SARS-CoV-2 infection in Paris

François Anna , Sophie Goyard , Ana Ines Lalanne , Fabien Nevo , Marion Gransagne , et al.
European Journal of Immunology, 2021, 51 (1), pp.180-190. ⟨10.1101/2020.10.25.20219030⟩
Article dans une revue pasteur-02988663v2
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Mechanisms of HIV-1 evasion to the antiviral activity of chemokine CXCL12 indicate potential links with pathogenesis

Marie Armani-Tourret , Zhicheng Zhou , Romain Gasser , Isabelle Staropoli , Vincent Cantaloube-Ferrieu , et al.
PLoS Pathogens, 2021, 17 (4), pp.e1009526. ⟨10.1371/journal.ppat.1009526⟩
Article dans une revue hal-03204143v1
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Deep phenotypic characterization of immunization-induced antibacterial IgG repertoires in mice using a single-antibody bioassay

Millie Heo , Guilhem Chenon , Carlos Castrillon , Jérôme Bibette , Pierre Bruhns , et al.
Communications Biology, 2020, 3 (1), pp.614. ⟨10.1038/s42003-020-01296-3⟩
Article dans une revue hal-03054253v1
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Tocilizumab-treated convalescent COVID-19 patients retain the cross-neutralization potential against SARS-CoV-2 variants

Camille Chauvin , Laurine Levillayer , Mathilde Roumier , Hubert Nielly , Claude Roth , et al.
iScience, 2023, 26 (3), pp.106124. ⟨10.1016/j.isci.2023.106124⟩
Article dans une revue hal-04090334v1
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Epitope convergence of broadly HIV-1 neutralizing IgA and IgG antibody lineages in a viremic controller

Valerie Lorin , Ignacio Fernández , Guillemette Masse-Ranson , Mélanie Bouvin-Pley , Luis M. Molinos-Albert , et al.
Journal of Experimental Medicine, 2022, 219 (3), pp.e20212045. ⟨10.1084/jem.20212045⟩
Article dans une revue pasteur-03654254v1
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Distinct evolution of SARS-CoV-2 Omicron XBB and BA.2.86/JN.1 lineages combining increased fitness and antibody evasion

Delphine Planas , Isabelle Staropoli , Vincent Michel , Frederic Lemoine , Flora Donati , et al.
Nature Communications, 2024, 15 (1), pp.2254. ⟨10.1038/s41467-024-46490-7⟩
Article dans une revue pasteur-04530809v1
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Temperature sensitivity of bat antibodies links metabolic state of bats with antigen-recognition diversity

Nia Toshkova , Violeta Zhelyzkova , Alejandra Reyes-Ruiz , Eline Haerens , Marina de Castro Deus , et al.
Nature Communications, 2024, 15 (1), pp.5878. ⟨10.1038/s41467-024-50316-x⟩
Article dans une revue pasteur-04675437v1
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Distinct systemic and mucosal immune responses during acute SARS-CoV-2 infection

Nikaïa Smith , Pedro Goncalves , Bruno Charbit , Ludivine Grzelak , Maxime Beretta , et al.
Nature Immunology, 2021, ⟨10.1038/s41590-021-01028-7⟩
Article dans une revue pasteur-03384279v1
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Qualitative monitoring of SARS-CoV-2 mRNA vaccination in humans using droplet microfluidics

Matteo Broketa , Aurélien Sokal , Michael Mor , Pablo Canales-Herrerias , Angga Perima , et al.
JCI Insight, 2023, In press. ⟨10.1172/jci.insight.166602⟩
Article dans une revue pasteur-04111772v1

Single-cell deep phenotyping of IgG-secreting cells for high-resolution immune monitoring

Klaus Eyer , Raphaël C L Doineau , Carlos E Castrillon , Luis Briseño-Roa , Vera Menrath , et al.
Nature Biotechnology, 2017, 35 (10), pp.977 - 982. ⟨10.1038/nbt.3964⟩
Article dans une revue hal-01639647v1
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HIV-1 Envelope Recognition by Polyreactive and Cross-Reactive Intestinal B Cells

Cyril Planchais , Ayrin Kök , Alexia Kanyavuz , Valérie Lorin , Timothée Bruel , et al.
Cell Reports, 2019, 27 (2), pp.572-585.e7. ⟨10.1016/j.celrep.2019.03.032⟩
Article dans une revue hal-02102470v1

Anti-V1/V3-glycan broadly HIV-1 neutralizing antibodies in a post-treatment controller

Luis M Molinos-Albert , Eduard Baquero , Mélanie Bouvin-Pley , Valerie Lorin , Caroline Charre , et al.
Cell Host & Microbe, 2023, 31 (8), pp.1275-1287.e8. ⟨10.1016/j.chom.2023.06.006⟩
Article dans une revue pasteur-04168501v1
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Are changes in antibiotic prophylaxis recommendations responsible for an increased risk of cefazolin allergy?

Nicolas Chéron , Luc de Chaisemartin , Simon Aubert , Felix Laborier , Philippe Montravers , et al.
Anaesthesia Critical Care & Pain Medicine, 2024, 43 (2), pp.101349. ⟨10.1016/j.accpm.2024.101349⟩
Article dans une revue hal-04613133v1
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A monocyte/dendritic cell molecular signature of SARS-CoV-2-related multisystem inflammatory syndrome in children with severe myocarditis

Camille de Cevins , Marine Luka , Nikaïa Smith , Sonia Meynier , Aude Magérus , et al.
Med, 2021, 2 (9), pp.1072-1092.e7. ⟨10.1016/j.medj.2021.08.002⟩
Article dans une revue hal-03590894v1
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Impact of Antigen Density on the Binding Mechanism of IgG Antibodies

Maya Hadzhieva , Anastas D. Pashov , Srinivas Kaveri , Sébastien Lacroix-Desmazes , Hugo Mouquet , et al.
Scientific Reports, 2017, 7, pp.3767. ⟨10.1038/s41598-017-03942-z⟩
Article dans une revue pasteur-01570226v1

Considerable escape of SARS-CoV-2 Omicron to antibody neutralization

Delphine Planas , Nell Saunders , Piet Maes , Florence Guivel-Benhassine , Cyril Planchais , et al.
Nature, 2022, 602 (7898), pp.671-675. ⟨10.1038/s41586-021-04389-z⟩
Article dans une revue pasteur-03654259v1
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Potent human broadly neutralizing antibodies to hepatitis B virus from natural controllers

Verena Hehle , Maxime Beretta , M Bourgine , Malika Ait-Goughoulte , Cyril Planchais , et al.
Journal of Experimental Medicine, 2020, 217 (10), pp.e20200840. ⟨10.1084/jem.20200840⟩
Article dans une revue pasteur-03242779v1
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IgG subclass-dependent pulmonary antigen retention during acute IgG-dependent systemic anaphylaxis in mice

Biliana Todorova , Ophélie Godon , Eva Conde , Caitlin Gillis , Bruno Iannascoli , et al.
Journal of Immunology, 2022, 209 (7), pp.1243-1251. ⟨10.4049/jimmunol.2200234⟩
Article dans une revue pasteur-04222570v1
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TLR9 signalling in HCV-associated atypical memory B cells triggers Th1 and rheumatoid factor autoantibody responses

Cloe Comarmond , Valerie Lorin , Cindy Marques , Anna Maciejewski-Duval , Nizar Joher , et al.
Journal of Hepatology, 2019, 71 (5), pp.908-919. ⟨10.1016/j.jhep.2019.06.029⟩
Article dans une revue pasteur-02625810v1
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Sec22b is a critical and non-redundant regulator of plasma cell maintenance

Amélie Bonaud , Laetitia Gargowitsch , Simon M Gilbert , Elanchezhian Rajan , Pablo Canales-Herrerias , et al.
Proceedings of the National Academy of Sciences of the United States of America, 2023, 120 (2), pp.e2213056120. ⟨10.1073/pnas.2213056120⟩
Article dans une revue hal-04064289v2

Reduced sensitivity of SARS-CoV-2 variant Delta to antibody neutralization

Delphine Planas , David Veyer , Artem Baidaliuk , Isabelle Staropoli , Florence Guivel-Benhassine , et al.
Nature, 2021, 596 (7871), pp.276-280. ⟨10.1038/s41586-021-03777-9⟩
Article dans une revue pasteur-03696844v1

Serum neutralization of SARS-CoV-2 Omicron sublineages BA.1 and BA.2 in patients receiving monoclonal antibodies

Olivier Schwartz , Thierry Prazuck , Benjamin Terrier , Emmanuel André , Etienne Simon-Loriere , et al.
Nature Medicine, 2022, ⟨10.1038/s41591-022-01792-5⟩
Article dans une revue pasteur-03654237v1
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Fusogenicity and neutralization sensitivity of the SARS-CoV-2 Delta sublineage AY.4.2

Nell Saunders , Delphine Planas , William Bolland , Christophe Rodriguez , Slim Fourati , et al.
EBioMedicine, 2022, 77, pp.103934. ⟨10.1016/j.ebiom.2022.103934⟩
Article dans une revue pasteur-03654246v1

Functional analysis via standardized whole-blood stimulation systems defines the boundaries of a healthy immune response to complex stimuli.

Darragh Duffy , Vincent Rouilly , Valentina Libri , Milena Hasan , Benoit Beitz , et al.
Immunity, 2014, 40 (3), pp.436-50. ⟨10.1016/j.immuni.2014.03.002⟩
Article dans une revue pasteur-01384537v1
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High-affinity autoreactive plasma cells disseminate through multiple organs in patients with immune thrombocytopenic purpura

Pablo Canales-Herrerias , Etienne Crickx , Matteo Broketa , Aurélien Sokal , Guilhem Chenon , et al.
The Journal of clinical investigation, 2022, ⟨10.1172/JCI153580⟩
Article dans une revue pasteur-03669881v1
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HIV-1 treatment timing shapes the human intestinal memory B-cell repertoire to commensal bacteria

Cyril Planchais , Luis M Molinos-Albert , Pierre Rosenbaum , Thierry Hieu , Alexia Kanyavuz , et al.
Nature Communications, 2023, 14 (1), pp.6326. ⟨10.1038/s41467-023-42027-6⟩
Article dans une revue hal-04248132v1
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MUB40 Binds to Lactoferrin and Stands as a Specific Neutrophil Marker

Mark C. Anderson , Thibault Chaze , Yves-Marie Coïc , Louise Injarabian , Friederike Jönsson , et al.
Cell Chemical Biology, 2018, 25 (4), pp.483-493.e9. ⟨10.1016/j.chembiol.2018.01.014⟩
Article dans une revue pasteur-02573125v1