COVID-19 and beyond: a call for action and audacious solidarity to all the citizens and nations, it is humanity’s fight
Charles Auffray
(1)
,
Rudi Balling
(2)
,
Niklas Blomberg
(3)
,
Myrna Bonaldo
(4)
,
Bertrand Boutron
,
Samir Brahmachari
(5)
,
Christian Bréchot
(6)
,
Alfredo Cesario
(7)
,
Sai-Juan Chen
(8)
,
Karine Clément
(9)
,
Daria Danilenko
(10)
,
Alberto Di Meglio
(11)
,
Andrea Gelemanović
(12)
,
Carole Goble
(13)
,
Takashi Gojobori
(14, 15)
,
Jason Goldman
(16)
,
Michel Goldman
(17)
,
Yi-Ke Guo
(18, 19)
,
James Heath
(20)
,
Leroy Hood
,
Peter Hunter
(21)
,
Li Jin
(22)
,
Hiroaki Kitano
(23, 24)
,
Bartha Knoppers
(25)
,
Doron Lancet
(26)
,
Catherine Larue
(27)
,
Mark Lathrop
,
Martine Laville
(28)
,
Ariel Lindner
(29)
,
Antoine Magnan
(30)
,
Andres Metspalu
(31)
,
Edgar Morin
(32)
,
Lisa F.P. Ng
,
Laurent Nicod
,
Denis Noble
,
Laurent Nottale
(33)
,
Helga Nowotny
,
Theresa Ochoa
(34)
,
Iruka Okeke
(35)
,
Tolu Oni
(36, 37)
,
Peter Openshaw
(18)
,
Mehmet Oztürk
(38)
,
Susanna Palkonen
,
Janusz Paweska
,
Christophe Pison
(39)
,
Mihael Polymeropoulos
,
Christian Pristipino
,
Ulrike Protzer
(40)
,
Josep Roca
,
Damjana Rozman
,
Marc Santolini
(29)
,
Ferran Sanz
,
Giovanni Scambia
,
Eran Segal
,
Ismail Serageldin
(41)
,
Marcelo Bento Soares
(42)
,
Peter Sterk
(43)
,
Sumio Sugano
(44, 45)
,
Giulio Superti-Furga
(46)
,
David Supple
,
Jesper Tegner
(14, 47)
,
Mathias Uhlen
(48)
,
Andrea Urbani
,
Alfonso Valencia
(49)
,
Vincenzo Valentini
(7)
,
Sylvie van der Werf
(50, 51)
,
Manlio Vinciguerra
(52)
,
Olaf Wolkenhauer
(53)
,
Emiel Wouters
(54, 55)
1
EISBM -
European Institute for Systems Biology and Medicine
2 uni.lu - Université du Luxembourg = University of Luxembourg = Universität Luxemburg
3 ELIXIR Hub [Cambridge]
4 FIOCRUZ - Fundação Oswaldo Cruz / Oswaldo Cruz Foundation
5 IGIB - CSIR Institute of Genomics and Integrative Biology [New Delhi]
6 Global Virus Network
7 FPUAG - Fondazione Policlinico Universitario A. Gemelli [Rome]
8 Shanghai Jiao Tong University School of Medicine
9 Nutriomics - Nutrition et obésités: approches systémiques (UMR-S 1269)
10 Smorodintsev Research Institute of Influenza [Saint-Petersbourg, Russia]
11 CERN - European Organization for Nuclear Research
12 MedILS - Mediterranean Institute for Life Sciences [Split, Croatia]
13 University of Manchester [Manchester]
14 KAUST - King Abdullah University of Science and Technology [Saudi Arabia]
15 NIG - National Institute of Genetics [Mishima, Japan]
16 Providence St Joseph Health [Seattle]
17 ULB - Université libre de Bruxelles
18 Imperial College London
19 HKBU - Hong Kong Baptist University
20 ISB - Institute for Systems Biology [Seattle]
21 University of Auckland [Auckland]
22 Fudan University [Shanghai]
23 SBI - The Systems Biology Institute [Tokyo]
24 OIST - Okinawa Institute of Science and Technology Graduate University
25 McGill University = Université McGill [Montréal, Canada]
26 Weizmann Institute of Science [Rehovot, Israël]
27 LIH - Luxembourg Institute of Health
28 CHLS - Centre Hospitalier Lyon Sud [CHU - HCL]
29 CRI - Centre de Recherche Interdisciplinaire / Center for Research and Interdisciplinarity [Paris, France]
30 ITSN - PHU 2 - Institut du Thorax et du Sytème Nerveux [CHU Nantes]
31 University of Tartu
32 Association pour la Pensée Complexe [Montpellier]
33 OBSPM - Observatoire de Paris - Site de Meudon
34 UPCH - Universidad Peruana Cayetano Heredia
35 University of Ibadan
36 University of Cambridge School of Clinical Medicine
37 University of Cape Town
38 DEÜ - Dokuz Eylül Üniversitesi = Dokuz Eylül University [Izmir]
39 UGA - Université Grenoble Alpes
40 TUM - Technische Universität Munchen - Technical University Munich - Université Technique de Munich
41 Bibliotheca Alexandrina - Library of Alexandria
42 University of Illinois College of Medicine
43 UvA - University of Amsterdam [Amsterdam] = Universiteit van Amsterdam
44 UTokyo - The University of Tokyo
45 OUJ - The Open University of Japan [Chiba]
46 Medizinische Universität Wien = Medical University of Vienna
47 KUH - Karolinska University Hospital [Solna, Sweden]
48 KTH - KTH Royal Institute of Technology [Stockholm]
49 BSC-CNS - Barcelona Supercomputing Center - Centro Nacional de Supercomputacion
50 GMV-ARN (UMR_3569 / U-Pasteur_2) - Génétique Moléculaire des Virus à ARN - Molecular Genetics of RNA Viruses
51 CNR - laboratoire coordonnateur - Centre National de Référence des virus des infections respiratoires (dont la grippe) - National Reference Center Virus Influenzae [Paris]
52 St. Anne’s University Hospital [Brno]
53 University of Rostock
54 Maastricht University [Maastricht]
55 Ludwig Boltzmann Institute for Lung Health [Vienna, Austria]
2 uni.lu - Université du Luxembourg = University of Luxembourg = Universität Luxemburg
3 ELIXIR Hub [Cambridge]
4 FIOCRUZ - Fundação Oswaldo Cruz / Oswaldo Cruz Foundation
5 IGIB - CSIR Institute of Genomics and Integrative Biology [New Delhi]
6 Global Virus Network
7 FPUAG - Fondazione Policlinico Universitario A. Gemelli [Rome]
8 Shanghai Jiao Tong University School of Medicine
9 Nutriomics - Nutrition et obésités: approches systémiques (UMR-S 1269)
10 Smorodintsev Research Institute of Influenza [Saint-Petersbourg, Russia]
11 CERN - European Organization for Nuclear Research
12 MedILS - Mediterranean Institute for Life Sciences [Split, Croatia]
13 University of Manchester [Manchester]
14 KAUST - King Abdullah University of Science and Technology [Saudi Arabia]
15 NIG - National Institute of Genetics [Mishima, Japan]
16 Providence St Joseph Health [Seattle]
17 ULB - Université libre de Bruxelles
18 Imperial College London
19 HKBU - Hong Kong Baptist University
20 ISB - Institute for Systems Biology [Seattle]
21 University of Auckland [Auckland]
22 Fudan University [Shanghai]
23 SBI - The Systems Biology Institute [Tokyo]
24 OIST - Okinawa Institute of Science and Technology Graduate University
25 McGill University = Université McGill [Montréal, Canada]
26 Weizmann Institute of Science [Rehovot, Israël]
27 LIH - Luxembourg Institute of Health
28 CHLS - Centre Hospitalier Lyon Sud [CHU - HCL]
29 CRI - Centre de Recherche Interdisciplinaire / Center for Research and Interdisciplinarity [Paris, France]
30 ITSN - PHU 2 - Institut du Thorax et du Sytème Nerveux [CHU Nantes]
31 University of Tartu
32 Association pour la Pensée Complexe [Montpellier]
33 OBSPM - Observatoire de Paris - Site de Meudon
34 UPCH - Universidad Peruana Cayetano Heredia
35 University of Ibadan
36 University of Cambridge School of Clinical Medicine
37 University of Cape Town
38 DEÜ - Dokuz Eylül Üniversitesi = Dokuz Eylül University [Izmir]
39 UGA - Université Grenoble Alpes
40 TUM - Technische Universität Munchen - Technical University Munich - Université Technique de Munich
41 Bibliotheca Alexandrina - Library of Alexandria
42 University of Illinois College of Medicine
43 UvA - University of Amsterdam [Amsterdam] = Universiteit van Amsterdam
44 UTokyo - The University of Tokyo
45 OUJ - The Open University of Japan [Chiba]
46 Medizinische Universität Wien = Medical University of Vienna
47 KUH - Karolinska University Hospital [Solna, Sweden]
48 KTH - KTH Royal Institute of Technology [Stockholm]
49 BSC-CNS - Barcelona Supercomputing Center - Centro Nacional de Supercomputacion
50 GMV-ARN (UMR_3569 / U-Pasteur_2) - Génétique Moléculaire des Virus à ARN - Molecular Genetics of RNA Viruses
51 CNR - laboratoire coordonnateur - Centre National de Référence des virus des infections respiratoires (dont la grippe) - National Reference Center Virus Influenzae [Paris]
52 St. Anne’s University Hospital [Brno]
53 University of Rostock
54 Maastricht University [Maastricht]
55 Ludwig Boltzmann Institute for Lung Health [Vienna, Austria]
Charles Auffray
- Fonction : Auteur
- PersonId : 1208692
- ORCID : 0000-0003-2226-7411
Bertrand Boutron
- Fonction : Auteur
- PersonId : 1254589
- ORCID : 0000-0001-5241-3462
Michel Goldman
- Fonction : Auteur
- PersonId : 1254590
- ORCID : 0000-0003-0222-7287
Leroy Hood
- Fonction : Auteur
Bartha Knoppers
- Fonction : Auteur
- PersonId : 1254591
- ORCID : 0000-0001-7004-2722
Mark Lathrop
- Fonction : Auteur
Lisa F.P. Ng
- Fonction : Auteur
Laurent Nicod
- Fonction : Auteur
Denis Noble
- Fonction : Auteur
Helga Nowotny
- Fonction : Auteur
Peter Openshaw
- Fonction : Auteur
- PersonId : 811606
- ORCID : 0000-0002-7220-2555
Susanna Palkonen
- Fonction : Auteur
Janusz Paweska
- Fonction : Auteur
Mihael Polymeropoulos
- Fonction : Auteur
Christian Pristipino
- Fonction : Auteur
Josep Roca
- Fonction : Auteur
Damjana Rozman
- Fonction : Auteur
Marc Santolini
- Fonction : Auteur
- PersonId : 752055
- IdHAL : msantolini
- ORCID : 0000-0003-1491-0120
- IdRef : 180719211
Ferran Sanz
- Fonction : Auteur
Giovanni Scambia
- Fonction : Auteur
Eran Segal
- Fonction : Auteur
David Supple
- Fonction : Auteur
Andrea Urbani
- Fonction : Auteur
Vincenzo Valentini
- Fonction : Auteur
- PersonId : 1254592
- ORCID : 0000-0003-4637-6487
Sylvie van der Werf
- Fonction : Auteur
- PersonId : 1202918
- IdHAL : sylvie-van-der-werf
- ORCID : 0000-0002-1148-4456
- IdRef : 070954534
Résumé
Background : Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) belongs to a subgroup of coronaviruses rampant in bats for centuries. It caused the coronavirus disease 2019 (COVID-19) pandemic. Most patients recover, but a minority of severe cases experience acute respiratory distress or an inflammatory storm devastating many organs that can lead to patient death. The spread of SARS-CoV-2 was facilitated by the increasing intensity of air travel, urban congestion and human contact during the past decades. Until therapies and vaccines are available, tests for virus exposure, confinement and distancing measures have helped curb the pandemic. Vision : The COVID-19 pandemic calls for safeguards and remediation measures through a systemic response. Self-organizing initiatives by scientists and citizens are developing an advanced collective intelligence response to the coronavirus crisis. Their integration forms Olympiads of Solidarity and Health. Their ability to optimize our response to COVID-19 could serve as a model to trigger a global metamorphosis of our societies with far-reaching consequences for attacking fundamental challenges facing humanity in the 21 st century. Mission : For COVID-19 and these other challenges, there is no alternative but action. Meeting in Paris in 2003, we set out to "rethink research to understand life and improve health." We have formed an international coalition of academia and industry ecosystems taking a systems medicine approach to understanding COVID-19 by thoroughly characterizing viruses, patients and populations during the pandemic, using openly shared tools. All results will be publicly available with no initial claims for intellectual property rights. This World Alliance for Health and Wellbeing will catalyze the creation of medical and health products such as diagnostic tests, drugs and vaccines that become common goods accessible to all, while seeking further alliances with civil society to bridge with socio-ecological and technological approaches that characterise urban systems, for a collective response to future health emergencies.
Domaines
Sciences du Vivant [q-bio]Origine | Publication financée par une institution |
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Licence |